您好,聚研生物科技敬请您关注以下信息:   [登录] [ 注册]

购物车



芯片及抗体专区

脂肪因子及肥胖症相关抗体芯片new!

详细信息:

       脂肪组织不再被看做是一个惰性能量储存器官,而是调控生理和病理过程的积极的参与者。从脂肪组织中鉴定出许多可溶性的因子,称之为脂肪细胞因子或者脂肪因子。一些脂肪因子如瘦素(leptin)和抵抗素(resistin)主要是由脂肪组织合成的,其他的脂肪因子如TNF-α,IL-6,MCP-1 和IL-1是在其他组织中合成。因为所有这些因子可以参与机制中的自分泌、旁分泌和内分泌过程。通常认为脂肪因子是肥胖、代谢综合症、糖尿病、炎症、免疫系统和其他的肥胖相关疾病的调控者。利用我们的夹心法免疫分析方法,研究者可以快速精确的检测一个样品中62个不同脂肪因子的表达水平。

编号
产品英文名
产品
中文名
特异性
产品描述
样品类型
载体
方法
AAH-ADI-1
RayBio® Human 
Adipokine  
Antibody Array 1 
人肥胖因子抗体芯片1
Human
可以同时检测62个人类细胞因子
血清、血浆、细胞培养上清、体液、细胞裂解液、组织裂解液
夹心法
标记法
AAH-ADI-G1
RayBio® Human 
Adipokine 
Antibody Array 1 
人肥胖因子抗体芯片1
Human
可以同时检测62个人类细胞因子
血清、血浆、细胞培养上清、体液、细胞裂解液、组织裂解液
夹心法标记法
QAH-ADI-1
Quantibody® Human Adipokine Array 1
人肥胖因子定量芯片1
Human
可以同时定量10个人类细胞因子
血清、血浆、细胞培养上清、体液、细胞裂解液、组织裂解液
夹心法
QAH-ADI-2
Quantibody® Human Adipokine Array 2
人肥胖因子定量芯片2
Human
可以同时定量4个人类肥胖因子
血清、血浆、细胞培养上清、体液、细胞裂解液、组织裂解液
夹心法

Product Focus: Adipokines & Obesity related products

      Introduction
  Obesity Frontier
  Adipokine Related Products Overview
  Adipokine Antibody Arrays: sandwich-based
  L Series Adipokine Arrays: Label based
  Quantibody Adipokine Arrays: Quantitative
  ELISA Kits 
  Antibody
  Enzyme Immunoassay (EIA) Based Kits
  Peptide
  Protein 
 

Introduction
Adipose tissue is no longer viewed as an inert energy storage organ, but is emerging as an active participant in regulating physiological and pathologic processes. Many soluble factors have been identified from the adipose tissue and are so called as adipocytokines or adipokines. Some of the adipokines are mainly produced by the adipose tisse like leptin and resistin, while others are also synthesized in other tissues like TNF-alpha, IL-6, MCP-1, and IL-1. Because all of these factors can act in an autocrine , paracrine or endocrine manner in the organisms, adipokines are thought to serve as mediators linking obesity, metabolic syndrome, diabetes, inflammation, immunity and other obesity-related diseases. 
 
Adipokine Antibody Arrays: sandwich-based (Cat# AAH-ADI-1 or AAH-ADI-G1)
As the protein array pioneer company, RayBiotech provides the most comprehensive cytokine antibody array products in today's market. Using our patent pending technology, researchers can rapidly and accurately measure the expression levels of 62 different adipokines from a single sample semi-quantitatively. The technology is designed based on the sandwich immunoassay principle. A panel of antibodies is immobilized in specific spot locations on the surface of membrane or a glass chip. Incubation of array membranes with biological samples results in the capture of adipokines by corresponding antibodies. The bound proteins are then detected with a cocktail of biotinylated antibodies. Finally, signals are visualized using chemiluminescence, colorimetry or fluorescence.

High Sensitivity: detects most proteins at pg levels

Affordable enough for routine use

High specificity

May be used with diverse biological samples

Customizable

Requires as little as 100 ul (membranes)
or 30 ul (glass chip)
Click for further information on all antibody array products.
Antibody List: 
4-1BB IGFPB-2 Leptin  PDGF-BB
ACE-2 IGFPB-3 Leptin R RANTES
Acrp30 IGF-I LIF Resistin
Adipsin IGF-1 sR Lymphotactin Serum Amyloid A
AgRP IL-1 R4/ST2 MCP-1 SDF-1
Ang-2 IL-1 sRI MCP-3 sTNF RII
Angiopoietin-1 IL-10 MCSF sTNT RI
ANGPTL4 IL-11 MIF TECK
CRP IL-12 MIP-1beta TGF-beta
ENA-78 IL-1 alpha MSP a-chain TIMP-1
Fas  IL-1 beta OPG TIMP-2
FGF-6 IL-6 OSM TNF-alpha
Growth Hormone IL-6 sR PAI-I VEGF
HCC-4 IL-8 PARC XEDAR
IFN-gamma Insulin PDGF-AA  
IGFBP-1 IP-10 PDGF-AB  
L-Series Adipokine Arrays: Label-based
Recent technological advances by RayBiotech have enabled the largest commercially available antibody array to date. With the L Series Antibody Array, researchers can now obtain a broad, panoramic view of cytokine expression. The expression levels of 182 human adipokines can be simultaneously detected in cell culture supernates or serum. Furthermore, an internal control is used to monitor the whole process including biotin-labeling, so this high density array will accurately reflect available adipokines in your sample.
 
 
 
 
 
 

  Back to top

Antibody List:

  Target Protein   Target Protein   Target Protein
1 ACE / CD43 62 Ghrelin 123 Neurophilin-2
2 ACE-2 63 GITR 124 NGF R
3 ACTH 64 GITRL 125 NPY (Neuropeptide Y)
4 ADFP 65 GLP-1  126 Obestatin R (GPR-39)
5 Adiponectin / Acrp30 66 Glucagon 127 Orexin A
6 Adipsin (Factor D) 67 Glut1 128 Orexin B
7 AgRP  68 Glut2 129 OSM
8 AMPKa1  69 Glut3 130 Osteocalcin
9 Amylin 70 Glut5 131 Osteonectin 
10 Angiopoietin-1 71 Glutathione peroxidase 1 132 Osteoprotegerin
11 Angiopoietin-2 72 Glutathione peroxidase 3 133 PARC
12 Angiotensinogen / Angiotensin II 73 GROa 134 PDGF
13 Ang-like Factor 74 HCC4 135 PDGF-AA
14 ANGPTL1 75 HGF 136 PDGF-AB
15 ANGPTL2 76 HSD-1 137 PDGF-C
16 ANGPTL3 77 ICAM1 138 PDGF-D
17 ANGPTL4  78 IFNg 139 PEDF 
18 Apelin Receptor  79 IGF-1 140 Pentraxin-3
19 ApoB 80 IGF-1 sR 141 PPARg2 / NRIC3
20 ApoE 81 IGFBP-1 142 Pref-1 
21 Axl 82 IGFBP-2 143 Prohibitin
22 BDNF 83 IGFBP-3 144 Prolactin
23 bFGF 84 IGF-II 145 PYY 
24 BMP-2  85 IL-1 R1 146 RANTES
25 BMP-3 86 IL-1 R4 147 RBP4 
26 BMP-3b / GDF-10 87 IL-1a 148 RELMb 
27 BMP-4  88 IL-1b 149 Resistin
28 BMP-5 89 IL-1ra 150 S100
29 BMP-6 90 IL-6 151 S100 A8+A9
30 BMP-7 91 IL-6 sR 152 S100 A10
31 BMP-8 92 IL-8 153 SAA 
32 BMP-15 93 IL-10 154 SDF-1
33 BMPR-IA / ALK-3 94 IL-11 155 SEMA3A
34 BMPR-IB / ALK-6

发布日期:2010-9-7 【返回】